Hormone Replacement Therapy in Seoul | Nucellin (Seoul Orthopedic Clinic)

At Nucellin (Seoul Orthopedic Clinic), we provide personalized hormone replacement therapy (HRT) as part of a holistic approach to restoring balance, vitality, and quality of life. Our protocols combine medical supervision, diagnostic precision, and ongoing monitoring to safely address hormonal deficiencies.

What Is Hormone Replacement Therapy?

Hormone replacement therapy involves administering hormones (e.g. estrogen, progesterone, testosterone, thyroid hormones) to restore levels that have declined due to aging, medical conditions, or endocrine dysfunction. The aim is to relieve symptoms, support metabolism, maintain bone and muscle health, and optimize overall wellness.

This is not just about symptom relief — properly balanced hormones can support energy, mood, sexual function, sleep, and physical resilience.

Ideal Candidates

  • Men experiencing low testosterone / andropause symptoms (low energy, reduced libido, muscle loss)
  • Women in perimenopause or menopause with estrogen/progesterone deficiency symptoms (hot flashes, mood swings, dryness)
  • People with hormonal imbalance due to thyroid or adrenal insufficiencies
  • Patients seeking a medical, monitored approach rather than over-the-counter hormonal supplements
  • Individuals willing to commit to lab testing, follow-up, and dose adjustments

Treatment Process Overview

1. Consultation & Hormonal Assessment

  • Detailed evaluation of symptoms, health history, and risk factors
  • Comprehensive blood panel: hormone levels (testosterone, estrogen, progesterone, LH, FSH, thyroid, DHEA, etc.)
  • Physical exam and discussion of goals, fertility desires, and contraindications

2. Personalized Protocol Design

  • Select the appropriate hormone(s), delivery method (oral, transdermal, injection, pellet)
  • Define starting dose and schedule tailored to your physiology

3. Initiation of Therapy

  • First dose or application under supervision
  • Instruction on how to administer (self-injection, topical application, etc.)

4. Monitoring & Titration

  • Regular lab checks (e.g. every 3–6 months initially) to monitor hormone levels, metabolic markers, liver function, lipids, and safety parameters
  • Adjust dose or method based on response, side effects, and lab values

5. Maintenance & Ongoing Management

  • Periodic symptom review, dose fine-tuning, and monitoring
  • Lifestyle support (nutrition, exercise, stress management) to complement therapy

Expected Timeline & Results

  • Many patients notice improved energy, mood, libido, sleep within weeks
  • Full benefits (muscle, bone, metabolism) often become more evident over 3–6 months
  • Hormonal balance is dynamic — dose adjustments may be needed over time

Risks & Considerations

  • Possible side effects: fluid retention, mood changes, acne, changes in lipid profile
  • Important safety monitoring: liver function, cardiovascular markers, prostate health (in men), breast health (in women)
  • Some conditions may contraindicate HRT (history of certain cancers, clotting disorders, uncontrolled cardiovascular disease)
  • Fertility can be suppressed depending on hormone regimen
  • Long-term safety depends on appropriate dosing, monitoring, and patient selection